ChExVis - A software tool for molecular channel extraction and visualization.
Understanding channel structures that lead to active sites or traverse a protein is important in the study of molecular functions such as ion, ligand, and small molecule transport. ChExVis implements an efficient algorithm for automatic identification of significant channels in a protein. The ChExVis web-server also supports interactive visual exploration of multiple channels together with their geometric and physico-chemical properties thereby enabling the understanding of the basic biology of transport through protein channels.
![](software/sws/channelsEx.png)
The transmembrane channels identified by ChExVis in the closed (2VL0) and open (3EAM) structures of pentametric ligand gated ion channel. The physico-chemical and conservation profiles are also shown along with the channels.
For more details, pease visit the web-server home-page here.
References
- Talha Bin Masood, Sankaran Sandhya, Nagasuma Chandra and Vijay Natarajan.
ChExVis: a tool for molecular channel extraction and visualization.
BMC Bioinformatics, 2015, 16:119.